Version history

{
  "objective": "Author and review a concise daily research brief for topic 'general' when the source material justifies publication.",
  "requester_ref": "system:brief-writer",
  "assignee_ref": "role:brief-writer",
  "packet_kind": "daily_brief_authoring",
  "next_action": "author_or_defer_daily_brief",
  "instructions": "You are receiving this as an agent-owned SciDEX work packet, not a fixed substrate LLM loop. Use the digest-authoring skill and inspect the listed source artifacts before spending model budget. Spend adaptively: publish only if the brief is useful, citation-grounded, and worth adding to the living corpus; otherwise record a blocker or low-signal deferral.\n\nTopic: general\nLookback: last 24h\nTarget length: 200-400 words.\nRequired sections if published: TL;DR, What's New, Open Questions, What to Read Next. Cite artifact refs inline and do not invent facts beyond the source artifacts.\n\nSource artifacts (10):\n- pantheon_debate:pd-d7b03b85242c1019: Do physiological concentrations of SCFAs (μM range) achieve therapeutic effects on α-synuclein clearance in vivo? — Analysis Notebook\n- pantheon_debate:pd-443bb16a90951e21: Does Alectinib truly bind C1q directly with high affinity, or is this an experimental artifact? — Analysis Notebook\n- pantheon_debate:pd-148bb7956703b133: How does parthenolide specifically modulate ADORA2A signaling to produce antidepressant effects? — Analysis Notebook\n- pantheon_debate:pd-0a360c1cc7a496ed: Does pericyte senescence drive BBB breakdown or result from neurodegeneration as a secondary response? — Analysis Notebook\n- pantheon_debate:pd-83933f5d56d6ced8: What specific autophagy pathways are defective in radiation-induced pericyte senescence? — Analysis Notebook\n- pantheon_debate:pd-878bf93b8a34af5d: Does restoring neuronal AMPK activity reverse microglial inflammation in vivo? — Analysis Notebook\n- pantheon_debate:pd-ec92af07b734f109: What determines the temporal sequence of cholinergic dysfunction versus amyloid/tau pathology in human AD? — Analysis Notebook\n- pantheon_debate:pd-5cbaf1c032d7dd20: Do pathogenic LRRK2 mutations amplify volume-sensing signals or just elevate baseline kinase activity? — Analysis Notebook\n- pantheon_debate:pd-6c7b08f823cba9f9: Does tau dendritic missorting persist independently after Aβ clearance, maintaining neurodegeneration? — Analysis Notebook\n- pantheon_debate:pd-5778bf9d2688a7cc: Does the cancer-cystatin-C-TREM2 pathway protect against tau pathology and other AD hallmarks beyond amyloid? — Analysis Notebook",
  "input_refs": [
    "pantheon_debate:pd-d7b03b85242c1019",
    "pantheon_debate:pd-443bb16a90951e21",
    "pantheon_debate:pd-148bb7956703b133",
    "pantheon_debate:pd-0a360c1cc7a496ed",
    "pantheon_debate:pd-83933f5d56d6ced8",
    "pantheon_debate:pd-878bf93b8a34af5d",
    "pantheon_debate:pd-ec92af07b734f109",
    "pantheon_debate:pd-5cbaf1c032d7dd20",
    "pantheon_debate:pd-6c7b08f823cba9f9",
    "pantheon_debate:pd-5778bf9d2688a7cc"
  ],
  "context_refs": {
    "topic": "general",
    "source_refs": [
      "pantheon_debate:pd-d7b03b85242c1019",
      "pantheon_debate:pd-443bb16a90951e21",
      "pantheon_debate:pd-148bb7956703b133",
      "pantheon_debate:pd-0a360c1cc7a496ed",
      "pantheon_debate:pd-83933f5d56d6ced8",
      "pantheon_debate:pd-878bf93b8a34af5d",
      "pantheon_debate:pd-ec92af07b734f109",
      "pantheon_debate:pd-5cbaf1c032d7dd20",
      "pantheon_debate:pd-6c7b08f823cba9f9",
      "pantheon_debate:pd-5778bf9d2688a7cc"
    ]
  },
  "acceptance_criteria": [
    "Inspect the source artifacts before authoring prose.",
    "Spend compute adaptively based on expected reader value.",
    "Publish at most one daily_brief wiki_page for this topic/date.",
    "Ground every substantive claim in source artifacts.",
    "Record blockers or low-signal deferrals explicitly."
  ],
  "deliverable_refs": [],
  "priority": "normal",
  "state": "requested",
  "roles": [
    "brief_writer",
    "scientific_reviewer"
  ],
  "role_aliases": [],
  "source_policy": "scheduled_worker:brief_writer_daily",
  "source_run_id": "sw-briefwriterd-3f7959d92994",
  "source_packet_id": "brief_writer_daily:2026-06-22:general",
  "signals": {
    "topic_delta": 10,
    "max_tokens_hint": 1500,
    "budget_reserved_usd": 1.5,
    "source_artifact_count": 10
  },
  "metadata": {
    "date": "2026-06-22",
    "topic": "general",
    "worker_name": "brief_writer_daily",
    "dispatch_mode": "agent_work_packet",
    "runtime_owner": "scidex-agents",
    "requested_budget": {
      "usd": 1.5
    },
    "budget_accounting": "scheduled_worker budget_usd_used records reserved agent-runtime budget for queued work, not direct substrate LLM spend"
  }
}