Version history

{
  "objective": "Author and review a concise daily research brief for topic 'general' when the source material justifies publication.",
  "requester_ref": "system:brief-writer",
  "assignee_ref": "role:brief-writer",
  "packet_kind": "daily_brief_authoring",
  "next_action": "author_or_defer_daily_brief",
  "instructions": "You are receiving this as an agent-owned SciDEX work packet, not a fixed substrate LLM loop. Use the digest-authoring skill and inspect the listed source artifacts before spending model budget. Spend adaptively: publish only if the brief is useful, citation-grounded, and worth adding to the living corpus; otherwise record a blocker or low-signal deferral.\n\nTopic: general\nLookback: last 24h\nTarget length: 200-400 words.\nRequired sections if published: TL;DR, What's New, Open Questions, What to Read Next. Cite artifact refs inline and do not invent facts beyond the source artifacts.\n\nSource artifacts (10):\n- pantheon_debate:pd-a8f449d500a4abef: Do physiological concentrations of SCFAs (μM range) achieve therapeutic effects on α-synuclein clearance in vivo? — Analysis Notebook\n- pantheon_debate:pd-c3879aa9697949fe: Does Alectinib truly bind C1q directly with high affinity, or is this an experimental artifact? — Analysis Notebook\n- pantheon_debate:pd-772c3e997c183a1e: How does parthenolide specifically modulate ADORA2A signaling to produce antidepressant effects? — Analysis Notebook\n- pantheon_debate:pd-42b6f59559077a72: Does pericyte senescence drive BBB breakdown or result from neurodegeneration as a secondary response? — Analysis Notebook\n- pantheon_debate:pd-3e77b1db124417d9: What specific autophagy pathways are defective in radiation-induced pericyte senescence? — Analysis Notebook\n- pantheon_debate:pd-6d4def9247234a17: Does restoring neuronal AMPK activity reverse microglial inflammation in vivo? — Analysis Notebook\n- pantheon_debate:pd-16a7a97768921eb5: What determines the temporal sequence of cholinergic dysfunction versus amyloid/tau pathology in human AD? — Analysis Notebook\n- pantheon_debate:pd-c2ed03b87c4f8ab6: Do pathogenic LRRK2 mutations amplify volume-sensing signals or just elevate baseline kinase activity? — Analysis Notebook\n- pantheon_debate:pd-bf2878be95e35f7e: Does tau dendritic missorting persist independently after Aβ clearance, maintaining neurodegeneration? — Analysis Notebook\n- pantheon_debate:pd-87b69124825b8681: Does the cancer-cystatin-C-TREM2 pathway protect against tau pathology and other AD hallmarks beyond amyloid? — Analysis Notebook",
  "input_refs": [
    "pantheon_debate:pd-a8f449d500a4abef",
    "pantheon_debate:pd-c3879aa9697949fe",
    "pantheon_debate:pd-772c3e997c183a1e",
    "pantheon_debate:pd-42b6f59559077a72",
    "pantheon_debate:pd-3e77b1db124417d9",
    "pantheon_debate:pd-6d4def9247234a17",
    "pantheon_debate:pd-16a7a97768921eb5",
    "pantheon_debate:pd-c2ed03b87c4f8ab6",
    "pantheon_debate:pd-bf2878be95e35f7e",
    "pantheon_debate:pd-87b69124825b8681"
  ],
  "context_refs": {
    "topic": "general",
    "source_refs": [
      "pantheon_debate:pd-a8f449d500a4abef",
      "pantheon_debate:pd-c3879aa9697949fe",
      "pantheon_debate:pd-772c3e997c183a1e",
      "pantheon_debate:pd-42b6f59559077a72",
      "pantheon_debate:pd-3e77b1db124417d9",
      "pantheon_debate:pd-6d4def9247234a17",
      "pantheon_debate:pd-16a7a97768921eb5",
      "pantheon_debate:pd-c2ed03b87c4f8ab6",
      "pantheon_debate:pd-bf2878be95e35f7e",
      "pantheon_debate:pd-87b69124825b8681"
    ]
  },
  "acceptance_criteria": [
    "Inspect the source artifacts before authoring prose.",
    "Spend compute adaptively based on expected reader value.",
    "Publish at most one daily_brief wiki_page for this topic/date.",
    "Ground every substantive claim in source artifacts.",
    "Record blockers or low-signal deferrals explicitly."
  ],
  "deliverable_refs": [],
  "priority": "normal",
  "state": "requested",
  "roles": [
    "brief_writer",
    "scientific_reviewer"
  ],
  "role_aliases": [],
  "source_policy": "scheduled_worker:brief_writer_daily",
  "source_run_id": "sw-briefwriterd-d3bf5de04aaa",
  "source_packet_id": "brief_writer_daily:2026-09-14:general",
  "signals": {
    "topic_delta": 10,
    "max_tokens_hint": 1500,
    "budget_reserved_usd": 1.5,
    "source_artifact_count": 10
  },
  "metadata": {
    "date": "2026-09-14",
    "topic": "general",
    "worker_name": "brief_writer_daily",
    "dispatch_mode": "agent_work_packet",
    "runtime_owner": "scidex-agents",
    "requested_budget": {
      "usd": 1.5
    },
    "budget_accounting": "scheduled_worker budget_usd_used records reserved agent-runtime budget for queued work, not direct substrate LLM spend"
  }
}