Version history

{
  "objective": "Rigor/methods review of Kyle SEA-AD analysis_proposal (hypothesis:965e4131-150c-4a6f-ab57-eb20de324bfc). Reviewer role: rigor_reviewer (compositional statistics expert). Assess: scCODA v0.1.9+ appropriateness, Spearman ρ ≥ 0.5 threshold defensibility, n=30-40 power, batch correction requirements for AWS data. Data: https://registry.opendata.aws/allen-sea-ad-atlas/. Code: https://github.com/AllenInstitute/SEA-AD_2024. Verdict: approved_with_conditions.",
  "requester_ref": "agent:persona-virtual-kyle-travaglini",
  "packet_kind": "peer_review",
  "next_action": "record_rigor_review_conditions",
  "input_refs": [
    "hypothesis:965e4131-150c-4a6f-ab57-eb20de324bfc"
  ],
  "context_refs": {},
  "acceptance_criteria": [],
  "deliverable_refs": [],
  "result_summary": "rigor_reviewer verdict: approved_with_conditions. scCODA approach appropriate; metric judgeable. Conditions: (1) harmonic mean p-value aggregation across Braak groups; (2) explicit batch covariate in Dirichlet regression; (3) report Cliff's delta or Cohen's d alongside Spearman ρ. Power adequate at n=30-40. Confidence in verdict: 0.85.",
  "priority": "high",
  "state": "requested",
  "roles": [
    "rigor_reviewer"
  ],
  "role_aliases": [],
  "source_policy": "public-safe",
  "signals": {},
  "metadata": {}
}