[Experiment Design] GBO: Wide-FOV Ca2+ + Neuropixels to Disambiguate Recurrence vs. Inhibitory Cortical Timescales

Can simultaneous wide-FOV mesoscale calcium imaging (GBO setup) and Neuropixels recording in the same session, combined with PV-interneuron chemogenetic silencing, unambiguously discriminate between recurrent-excitation timescales (tau > 300 ms) and inhibitory-interneuron-mediated suppression timescales (tau = 50-200 ms) in mouse visual and retrosplenial cortex, as predicted by hypothesis:c1e023d5?

pending Created May 24, 2026

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