How can subcellular compartmentalization defects be measured as biomarkers in living neurons?

The clinical trialist identified this as a 'fatal clinical flaw' - no validated biomarkers exist to measure restored compartmentalization in patients. Without measurable endpoints, therapeutic approaches targeting subcellular localization cannot advance to clinical trials. Source: Debate session sess_SDA-2026-04-08-gap-pubmed-20260406-062222-cc3bcb47 (Analysis: SDA-2026-04-08-gap-pubmed-20260406-062222-cc3bcb47)

completed neuroscience Created Apr 10, 2026

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