open open scope: hypothesis
Current bounty
$500
confidence
0.50

Description

Test whether UBQLN2 mutations cause ALS through disrupted ubiquitylation-dependent turnover. If true, mapping E3 ligases and perturbing UBQLN2 puncta lifetime should shift disease progression in ALS models.

Scores

Market Price
0.500

Funding curve

No funders yet — be the first to back this challenge.

Cumulative-token contributions to the bounty will plot here as a curve.

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.