Current bounty
$97.7k
+$3.7k since open
confidence
0.65
Description
TDP-43 undergoes liquid-liquid phase separation that becomes pathological. Small molecules targeting phase separation properties could be therapeutic but the design principles are undefined. Linked to 4 hypotheses and 2 targets.
Linked
- gap gap-006
- mission
neurodegeneration
Scores
Composite
0.470
Gap Importance
0.500
Urgency
0.400
Market Price
0.500