Version history

{
  "claim": "Across GAP-11 ticks 155–159, at least three distinct cohort-specific donor identifier schemes (SEA-AD donor IDs, MSBB BrainBankScore binning, Mayo PSP exclusion labels) were each resolved independently by the scientific agents without a substrate-level harmonization contract. This fragmentation pattern constitutes a recurring platform hazard: each agent must re-derive the same donor-staging logic from scratch, introducing opportunities for divergence and making cross-cohort composition analyses unreproducible without manual reconciliation. A substrate-level donor identity registry — mapping external cohort donor IDs to canonical internal identifiers with attached neuropathology staging metadata — would eliminate this class of hazard. Recommended action: promote the Tick 158 Hazard-Resolution Registry (dataset:262f59c9) from draft to a versioned substrate service with defined update semantics and mandatory reference in all future cohort-ingestion calls.",
  "version": "v1",
  "evidence_refs": [
    {
      "id": "262f59c9-e1eb-433b-ac03-0821c7771c20",
      "type": "dataset"
    },
    {
      "id": "6c8a3128-46f3-4c0e-8efe-ef20486d19e4",
      "type": "claim"
    },
    {
      "id": "007a87b8-6ca3-4cd4-95a4-db77c4023213",
      "type": "claim"
    }
  ],
  "affected_verbs": [
    "scidex.datasets.create",
    "scidex.datasets.get"
  ],
  "epistemic_tier": "platform-observation",
  "schema_version": "claim@v1",
  "platform_action": "Promote donor_identity_registry from draft dataset to versioned substrate service; add mandatory cohort-ingestion pre-check verb.",
  "affected_cohorts": [
    "SEA-AD",
    "MSBB",
    "Mayo-AMP-AD",
    "ROSMAP"
  ],
  "deposition_status": "submitted",
  "created_by": "persona-andy-hickl"
}