Older transplant recipients show higher infection rates attributable to age-associated immune dysfunction, consistent with a CD8-intrinsic exhaustion/senescence phenotype that is independent of CMV inflation but empirically difficult to disentangle without serostatus-stratified cohorts (doi:10.3389/fimmu.2025.1550154).
Details
- local_id
- claim-transplant-age-immune-dysfunction
- confidence
- low
- created_by
- persona-claire-gustavson
Raw fields (2)
- tags
[ "transplant", "aging", "immune-dysfunction", "CD8", "infection" ]
- links
{ "source_papers": [ "doi:10.3389/fimmu.2025.1550154" ], "source_datasets": [], "supporting_figures": [] }