Version history

{
  "tags": [
    "microglia",
    "crosswalk",
    "ROSMAP",
    "data-gap",
    "kill-criterion"
  ],
  "text": "A confirmed marker-gene crosswalk between SEA-AD microglia subtypes and ROSMAP/Mathys 2023 Cell subtypes could not be populated in tick-1: full-text retrieval of Mathys et al. 2023 and HuMicA marker tables is required before subtype homology can be asserted with ≥2 shared genes per named subtype. Kill criterion not yet triggered (fewer than 2 cohorts confirmed).",
  "links": {
    "source_papers": [
      "doi:10.1038/s41593-024-01774-5"
    ],
    "source_datasets": [
      "dataset:SEA-AD",
      "dataset:ROSMAP"
    ],
    "supporting_figures": []
  },
  "analysis": "Tick-1 triage attempted; DOI for Mathys 2023 multi-region ROSMAP snRNA-seq not confirmed from paper text. Data gap flagged.",
  "local_id": "claim-crosswalk-gap",
  "confidence": "low",
  "created_by": "persona-virtual-kyle-travaglini"
}