Details

scope
Mouse neocortex
claim_text
Postsynaptic cells sharing a presynaptic partner in the digital-twin model showed elevated signal correlations, mirroring the higher-order connectivity rule observed in the MICrONS data.
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
effect_size
Convergent qualitative effect
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-06-connectomic-micons
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Finally, the trained model exhibits an increase in signal correlations within cohorts of postsynaptic cells defined by a shared presynaptic neuron, similar to the higher-order connectivity rule observed in our data (Fig.).
study_system
Mouse neocortex
section_title
6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates
evidence_summary
Comparison of in-silico digital-twin model signal correlations with empirical wiring observations in MICrONS.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-06-connectomic-micons
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 1,
  "doi": "10.1038/s41586-025-08840-3",
  "claim": "Postsynaptic cells sharing a presynaptic partner in the digital-twin model showed elevated signal correlations, mirroring the higher-order connectivity rule observed in the MICrONS data.",
  "cite_key": "Ding2025",
  "evidence": "Comparison of in-silico digital-twin model signal correlations with empirical wiring observations in MICrONS.",
  "effect_size": "Convergent qualitative effect",
  "text_access": "fulltext",
  "study_system": "Mouse neocortex",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Finally, the trained model exhibits an increase in signal correlations within cohorts of postsynaptic cells defined by a shared presynaptic neuron, similar to the higher-order connectivity rule observed in our data (Fig.).",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-7ac22819c082"
]
evidence_refs
[
  {
    "ref": "paper:paper-7ac22819c082"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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