- claim_text
Antidromic identification of IT and PT cortical neurons in rat showed that despite a 4.6-fold faster PT conduction velocity, striatonigral and striatopallidal SPNs had identical spike-response latencies to ipsilateral cortex stimulation, supporting the view that IT (not PT) is the dominant cortical input to both pathways.
- raw_fields
{
"n": null,
"doi": "10.1111/j.1460-9568.2008.06192.x",
"claim": "Antidromic identification of IT and PT cortical neurons in rat showed that despite a 4.6-fold faster PT conduction velocity, striatonigral and striatopallidal SPNs had identical spike-response latencies to ipsilateral cortex stimulation, supporting the view that IT (not PT) is the dominant cortical input to both pathways.",
"cite_key": "Ballion2008",
"evidence": "In vivo electrophysiology in rats with antidromic identification of IT vs PT corticostriatal neurons and identification of striatonigral vs striatopallidal SPNs.",
"effect_size": "PT conduction velocity = 4.6× IT; latencies of striatonigral vs striatopallidal SPNs to ipsilateral cortical stimulation: identical",
"text_access": "abstract_only",
"study_system": "rat (in vivo extracellular electrophysiology with antidromic identification)",
"source_cluster_id": "cluster_03",
"replication_status": "contested",
"claim_source_sentence": "Firstly, although the conduction velocity of PT neurons is 4.6 times faster than that of IT neurons, identified striatopallidal and striatonigral neurons exhibit identical latencies of their spike responses to electrical stimulation of the ipsilateral cortex.",
"replication_evidence_dois": [
"10.1523/jneurosci.2660-08.2008",
"10.1126/sciadv.abh4315"
],
"effect_size_source_sentence": "Firstly, although the conduction velocity of PT neurons is 4.6 times faster than that of IT neurons, identified striatopallidal and striatonigral neurons exhibit identical latencies of their spike responses to electrical stimulation of the ipsilateral cortex."
}- source_refs
[
"paper:paper-c38c21fbb36c"
]
- source_span
Firstly, although the conduction velocity of PT neurons is 4.6 times faster than that of IT neurons, identified striatopallidal and striatonigral neurons exhibit identical latencies of their spike responses to electrical stimulation of the ipsilateral cortex.
- evidence_refs
[
{
"ref": "paper:paper-c38c21fbb36c"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}