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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse FC, S1, V1; immunohistochemistry", "claim_text": "VIP+ cells in mouse cortex are biased toward supragranular layers across multiple cortical regions: in frontal cortex, layer 2/3 contains ~62 VIP+/mm² versus ~22–30/mm² in other layers, with 32.6% of VIP+ cells in L2/3 versus 14–24% per layer in L1, L4–L6.", "raw_fields": { "n": 0, "doi": "10.1002/cne.22229", "claim": "VIP+ cells in mouse cortex are biased toward supragranular layers across multiple cortical regions: in frontal cortex, layer 2/3 contains ~62 VIP+/mm² versus ~22–30/mm² in other layers, with 32.6% of VIP+ cells in L2/3 versus 14–24% per layer in L1, L4–L6.", "title": null, "cite_key": "Xu2010a", "evidence": "Quantitative immunostaining across FC, S1, V1 in mouse.", "effect_size": "L2/3 VIP density 2–3× deeper layer densities", "text_access": "fulltext", "study_system": "mouse FC, S1, V1; immunohistochemistry", "_source_cluster": "cluster_03_morphology", "replication_status": "replicated", "_source_cluster_index": 30, "claim_source_sentence": "For example, in FC, the density of VIP+ cells in layer 2/3 was 62.1 ± 11.2/mm 2 , while the densities of layers 1, 4, 5 and 6 were 22.4 ± 6.9/mm 2 , 25.5 ± 20.7/mm 2 , 23.4 ± 3.7/mm 2 , and 29.8 ± 8.6/mm 2 , respectively.", "replication_evidence_dois": [ "10.3389/neuro.05.003.2007", "10.1002/dneu.20853" ], "effect_size_source_sentence": "The percentages of VIP+ cells for layers 1, 2/3 through 6 in FC were 16.4%, 32.6%, 24.1%, 12.5% and 14.3%, respectively." }, "section_id": "section_04", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json", "effect_size": "L2/3 VIP density 2–3× deeper layer densities", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-04-morphology", "source_kind": "review_finding", "source_path": "evidence/section_04_evidence_package.json", "source_refs": [ "paper:paper-f74768c3fc02" ], "source_span": "For example, in FC, the density of VIP+ cells in layer 2/3 was 62.1 ± 11.2/mm 2 , while the densities of layers 1, 4, 5 and 6 were 22.4 ± 6.9/mm 2 , 25.5 ± 20.7/mm 2 , 23.4 ± 3.7/mm 2 , and 29.8 ± 8.6/mm 2 , respectively.", "study_system": "mouse FC, S1, V1; immunohistochemistry", "evidence_refs": [ { "ref": "paper:paper-f74768c3fc02" } ], "section_title": "Morphological Diversity", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Quantitative immunostaining across FC, S1, V1 in mouse.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-04-morphology", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }