- claim_text
In Parkinson's patients off medication, GPi and STN local potentials are dominated by coherent <30 Hz (beta-range) oscillations and levodopa shifts the spectral peak to ~70 Hz, demonstrating dopamine-dependent oscillatory coupling between basal ganglia output nuclei.
- raw_fields
{
"n": 4,
"doi": "10.1523/jneurosci.21-03-01033.2001",
"claim": "In Parkinson's patients off medication, GPi and STN local potentials are dominated by coherent <30 Hz (beta-range) oscillations and levodopa shifts the spectral peak to ~70 Hz, demonstrating dopamine-dependent oscillatory coupling between basal ganglia output nuclei.",
"cite_key": "Brown2001",
"evidence": "",
"effect_size": "off-meds: <30 Hz coherence; on levodopa: shift to ~70 Hz peak",
"text_access": "abstract_only",
"study_system": "humans with PD undergoing DBS surgery, intra-operative GPi and STN local-potential recording",
"source_cluster_id": "cluster_04",
"replication_status": "independently_replicated",
"claim_source_sentence": "Without medication, the power within and the coherence between the GPi and STN was dominated by activity with a frequency <30 Hz.",
"replication_evidence_dois": [
"10.1523/jneurosci.4199-08.2008",
"10.1111/j.1460-9568.2006.04717.x"
],
"effect_size_source_sentence": "Without medication, the power within and the coherence between the GPi and STN was dominated by activity with a frequency <30 Hz."
}- source_refs
[
"paper:paper-7f1c9a89fbd7"
]
- evidence_refs
[
{
"ref": "paper:paper-7f1c9a89fbd7"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}