Details

scope
basal-ganglia
claim_text
Cholinergic interneurons (ChIs) make up only 1–2% of all neurons in the striatum ( Dopico et al., 1998 ), but play an outsize role in regulating NAc GABAergic ( Melendez-Zaidi et al., 2019 ), glutamatergic ( Higley et...
section_id
section_10
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_10_evidence_package.json
effect_size
2%
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-10
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
study_system
section_title
Dopaminergic Modulation of Loop Dynamics
evidence_summary
primary_experimental
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-10
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_10_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.3389/fncel.2022.1010121",
  "claim": "Cholinergic interneurons (ChIs) make up only 1–2% of all neurons in the striatum ( Dopico et al., 1998 ), but play an outsize role in regulating NAc GABAergic ( Melendez-Zaidi et al., 2019 ), glutamatergic ( Higley et...",
  "cite_key": "Kolpakova2022",
  "evidence": "primary_experimental",
  "effect_size": "2%",
  "text_access": "fulltext",
  "study_system": "",
  "source_cluster_id": "cluster_09",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Cholinergic interneurons (ChIs) make up only 1–2% of all neurons in the striatum ( Dopico et al., 1998 ), but play an outsize role in regulating NAc GABAergic ( Melendez-Zaidi et al., 2019 ), glutamatergic ( Higley et al., 2011 ; Assous, 2021 ) and dopaminergic synaptic transmission ( Threlfell et al., 2012 ; Collins et al., 2016 ) through their extensive projections ( Lim et al., 2014 ).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Cholinergic interneurons (ChIs) make up only 1–2% of all neurons in the striatum ( Dopico et al., 1998 ), but play an outsize role in regulating NAc GABAergic ( Melendez-Zaidi et al., 2019 ), glutamatergic ( Higley et al., 2011 ; Assous, 2021 ) and dopaminergic synaptic transmission ( Threlfell et al., 2012 ; Collins et al., 2016 ) through their extensive projections ( Lim et al., 2014 )."
}
source_refs
[
  "paper:paper-a61da55e754b"
]
source_span
Cholinergic interneurons (ChIs) make up only 1–2% of all neurons in the striatum ( Dopico et al., 1998 ), but play an outsize role in regulating NAc GABAergic ( Melendez-Zaidi et al., 2019 ), glutamatergic ( Higley et al., 2011 ; Assous, 2021 ) and dopaminergic synaptic transmission ( Threlfell et al., 2012 ; Collins et al., 2016 ) through their extensive projections ( Lim et al., 2014 ).
evidence_refs
[
  {
    "ref": "paper:paper-a61da55e754b"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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