Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affec…

Details

scope: basal-ganglia
claim_text: Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affects the expression, availability, and affinity of the DRD2 receptors
section_id: section_10
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_10_evidence_package.json
effect_size: 15%
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-10
source_kind: review_finding
source_path: evidence/section_10_evidence_package.json
source_span: Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affects the expression, availability, and affinity of the DRD2 receptors.
study_system
section_title: Dopaminergic Modulation of Loop Dynamics
evidence_summary: primary_experimental
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-10
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_10_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.3389/fgene.2025.1610364",
  "claim": "Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affects the expression, availability, and affinity of the DRD2 receptors",
  "cite_key": "Chaudhary2025",
  "evidence": "primary_experimental",
  "effect_size": "15%",
  "text_access": "fulltext",
  "study_system": "",
  "source_cluster_id": "cluster_09",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affects the expression, availability, and affinity of the DRD2 receptors.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Results In the total 400 samples analyzed, the TT genotype and T allele frequencies were 15% and 43%, respectively."
}

source_refs

[
  "paper:paper-69b97ee57499"
]

evidence_refs

[
  {
    "ref": "paper:paper-69b97ee57499"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Although, Taq1A polymorphism is not located in the DRD2 gene, however, it affec…

Details

Replication

Discussion