Details
- scope
- Dravet syndrome review
- claim_text
- Dravet syndrome, caused by SCN1A loss-of-function mutations affecting PV interneurons, demonstrates the critical importance of Nav1.1 for interneuron function.
- section_id
- section_02_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-02
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- source_span
- Selective Nav1.1 Activation Rescues Dravet Syndrome Mice From Seizures and Premature Death.
- study_system
- Dravet syndrome review
- section_title
- Molecular Identity and Transcriptomic Taxonomy
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-02
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1177/1535759718822038", "claim": "Dravet syndrome, caused by SCN1A loss-of-function mutations affecting PV interneurons, demonstrates the critical importance of Nav1.1 for interneuron function.", "evidence": "", "effect_size": null, "text_access": "abstract_only", "study_system": "Dravet syndrome review", "replication_status": "independently_replicated", "claim_source_sentence": "Selective Nav1.1 Activation Rescues Dravet Syndrome Mice From Seizures and Premature Death.", "replication_evidence_dois": [ "10.1073/pnas.1411131111", "10.1523/JNEUROSCI.0193-18.2018" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-096aa90cb265" ]
- evidence_refs
[ { "ref": "paper:paper-096aa90cb265" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }