In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton densit…

Details

scope: human dentate gyrus, mesial temporal lobe epilepsy
claim_text: In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton density increases while PVChC bouton density decreases in the dentate granule cell layer
section_id: section_04_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
effect_size: PVBC boutons increased, PVChC boutons decreased significantly in hippocampal sclerosis
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-04
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: We found increased density of PVBC boutons, while PVChC boutons decreased significantly in the dentate granule cell layer of subjects with hippocampal sclerosis compared with matched controls.
study_system: human dentate gyrus, mesial temporal lobe epilepsy
section_title: Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond
evidence_summary: In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton density increases while PVChC bouton density decreases in the dentate granule cell layer
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-04
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 15,
  "doi": "10.1152/jn.00523.2018",
  "claim": "In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton density increases while PVChC bouton density decreases in the dentate granule cell layer",
  "evidence": "In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton density increases while PVChC bouton density decreases in the dentate granule cell layer",
  "effect_size": "PVBC boutons increased, PVChC boutons decreased significantly in hippocampal sclerosis",
  "text_access": "fulltext",
  "study_system": "human dentate gyrus, mesial temporal lobe epilepsy",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found increased density of PVBC boutons, while PVChC boutons decreased significantly in the dentate granule cell layer of subjects with hippocampal sclerosis compared with matched controls.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "We found increased density of PVBC boutons, while PVChC boutons decreased significantly."
}

source_refs

[
  "paper:paper-026e39c932f7"
]

evidence_refs

[
  {
    "ref": "paper:paper-026e39c932f7"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

In mesial temporal lobe epilepsy with hippocampal sclerosis, PVBC bouton densit…

Details

Replication

Discussion