Version history

{
  "scope": "mouse Dravet Syndrome model, chandelier cells",
  "claim_text": "Chandelier cells in Dravet Syndrome show developmental dysregulation of excitability, assessed using cell type-specific enhancer elements",
  "raw_fields": {
    "n": null,
    "doi": "10.64898/2026.02.02.702918",
    "claim": "Chandelier cells in Dravet Syndrome show developmental dysregulation of excitability, assessed using cell type-specific enhancer elements",
    "evidence": "Chandelier cells in Dravet Syndrome show developmental dysregulation of excitability, assessed using cell type-specific enhancer elements",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "mouse Dravet Syndrome model, chandelier cells",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Chandelier cells (ChCs) are a rare and highly specialized subtype of inhibitory neuron in the cerebral cortex that specifically and exclusively form synapses onto the axon initial segment of excitatory neurons and thereby exert powerful control of excitability.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-04",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-e5cc445b7014"
  ],
  "source_span": "Chandelier cells (ChCs) are a rare and highly specialized subtype of inhibitory neuron in the cerebral cortex that specifically and exclusively form synapses onto the axon initial segment of excitatory neurons and thereby exert powerful control of excitability.",
  "study_system": "mouse Dravet Syndrome model, chandelier cells",
  "evidence_refs": [
    {
      "ref": "paper:paper-e5cc445b7014"
    }
  ],
  "section_title": "Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Chandelier cells in Dravet Syndrome show developmental dysregulation of excitability, assessed using cell type-specific enhancer elements",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-04",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}