- claim_text
We also performed whole-cell patch clamp recording of miniature inhibitory postsynaptic potentials (mIPSPs) in DLPFC slices prepared from pre- and postpubertal monkeys.<h4>Results</h4>The mRNA and protein levels of alpha1 and alpha2 subunits progress
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"n": 11,
"doi": "10.1016/j.biopsych.2009.01.004",
"claim": "We also performed whole-cell patch clamp recording of miniature inhibitory postsynaptic potentials (mIPSPs) in DLPFC slices prepared from pre- and postpubertal monkeys.<h4>Results</h4>The mRNA and protein levels of alpha1 and alpha2 subunits progress",
"evidence": "<h4>Background</h4>In schizophrenia, working memory dysfunction is associated with altered expression of gamma-aminobutyric acid (GABA)(A) receptor alpha1 and alpha2 subunits in the dorsolateral prefrontal cortex (DLPFC). In rodents, cortical alpha subunit expression shifts from low alpha1 and high ",
"effect_size": null,
"text_access": "fulltext",
"study_system": "rat cortex prefrontal cortex",
"replication_status": "replication_unknown",
"claim_source_sentence": "We also performed whole-cell patch clamp recording of miniature inhibitory postsynaptic potentials (mIPSPs) in DLPFC slices prepared from pre- and postpubertal monkeys.<h4>Results</h4>The mRNA and protein levels of alpha1 and alpha2 subunits progressively increased and decreased, respectively, throughout postnatal development including adolescence.",
"replication_evidence_dois": [],
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We also performed whole-cell patch clamp recording of miniature inhibitory postsynaptic potentials (mIPSPs) in DLPFC slices prepared from pre- and postpubertal monkeys.<h4>Results</h4>The mRNA and protein levels of alpha1 and alpha2 subunits progressively increased and decreased, respectively, throughout postnatal development including adolescence.
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"Local review repositories are read-only inputs.",
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<h4>Background</h4>In schizophrenia, working memory dysfunction is associated with altered expression of gamma-aminobutyric acid (GABA)(A) receptor alpha1 and alpha2 subunits in the dorsolateral prefrontal cortex (DLPFC). In rodents, cortical alpha subunit expression shifts from low alpha1 and high