Details
- scope
- mouse forelimb motor cortex (M1), both sexes
- section_id
- section_07
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
- effect_size
- qualitative — strong CT↔CT and CT↔IT vs. strikingly little CT↔PT
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-07-celltype-motifs
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B.
- study_system
- mouse forelimb motor cortex (M1), both sexes
- section_title
- 7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
- evidence_summary
- Photostimulation-based and paired electrophysiological recordings of retrogradely labeled CT/IT/PT neurons in mouse forelimb M1.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-07-celltype-motifs
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
In mouse motor cortex, paired-recording dissection of L6 CT, L5 IT and L5 PT projection neurons revealed strong CT↔CT and CT↔IT connections but strikingly little CT↔PT excitatory connectivity, with CT→IT connections restricted to L6 IT neurons rather than L5B IT.
- raw_fields
{ "n": 0, "doi": "10.1523/jneurosci.4023-14.2015", "claim": "In mouse motor cortex, paired-recording dissection of L6 CT, L5 IT and L5 PT projection neurons revealed strong CT↔CT and CT↔IT connections but strikingly little CT↔PT excitatory connectivity, with CT→IT connections restricted to L6 IT neurons rather than L5B IT.", "cite_key": "Yamawaki2015", "evidence": "Photostimulation-based and paired electrophysiological recordings of retrogradely labeled CT/IT/PT neurons in mouse forelimb M1.", "effect_size": "qualitative — strong CT↔CT and CT↔IT vs. strikingly little CT↔PT", "text_access": "abstract_only", "study_system": "mouse forelimb motor cortex (M1), both sexes", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1523/JNEUROSCI.2277-19.2020", "10.1523/ENEURO.0154-24.2024" ], "effect_size_source_sentence": "There was strikingly little CT↔ PT excitatory connectivity." }- source_refs
[ "paper:paper-77ff3f69a352" ]
- evidence_refs
[ { "ref": "paper:paper-77ff3f69a352" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }