- claim_text
A cortico-basal ganglia-thalamo-cortical channel through SNr supports selective persistent activity in mouse frontal cortex during short-term memory: optogenetic activation or inactivation of the SNr-to-thalamus pathway biases licking choice and selectively modulates neural trajectories encoding one of the two choices.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2021.08.002",
"claim": "A cortico-basal ganglia-thalamo-cortical channel through SNr supports selective persistent activity in mouse frontal cortex during short-term memory: optogenetic activation or inactivation of the SNr-to-thalamus pathway biases licking choice and selectively modulates neural trajectories encoding one of the two choices.",
"cite_key": "Wang2021b",
"evidence": "",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "mouse SNr–thalamus–frontal cortex CBTC circuit; optogenetic perturbations + electrophysiology during delayed-response licking",
"argument_role": "supporting",
"replication_status": "independently_replicated",
"claim_source_sentence": "Optogenetic activation or inactivation of the basal ganglia output nucleus substantia nigra pars reticulata (SNr)-to-thalamus pathway biased future licking choice, without affecting licking execution.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [
"10.1038/nature22324",
"10.1038/s41586-018-0633-x"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-c5f89ac422cb"
]
- evidence_refs
[
{
"ref": "paper:paper-c5f89ac422cb"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}