Strong feedback inhibition stabilizing recurrent excitation produces 'balanced…

Strong feedback inhibition stabilizing recurrent excitation produces 'balanced amplification' — selective, transient amplification of activity patterns via effective feedforward connectivity between E and I — providing an alternative to lifetime-elongation (slow-decay) explanations of evoked-vs-spontaneous similarity in cortex.

{
  "n": 0,
  "doi": "10.1016/j.neuron.2009.02.005",
  "claim": "Strong feedback inhibition stabilizing recurrent excitation produces 'balanced amplification' — selective, transient amplification of activity patterns via effective feedforward connectivity between E and I — providing an alternative to lifetime-elongation (slow-decay) explanations of evoked-vs-spontaneous similarity in cortex.",
  "cite_key": "Murphy2009",
  "evidence": "Establishes inhibition-stabilised cortex as a generic recurrent regime alternative to pure attractor amplification; mouse-cortex theory papers explicitly contrast ISN balanced amplification against bump-attractor amplification.",
  "effect_size": "qualitative",
  "text_access": "abstract_only",
  "study_system": "recurrent excitatory-inhibitory rate / spiking model of primary visual cortex (cat V1)",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Strong balanced amplification arises when feedback inhibition stabilizes strong recurrent excitation, a pattern likely to be typical of cortex.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.7554/elife.54875",
    "10.7554/elife.71263"
  ],
  "effect_size_source_sentence": null
}

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]

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  "notes": [
    "Local review repositories are read-only inputs.",
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