Details
- scope
- therapeutic targeting / PV circuits
- claim_text
- Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments
- section_id
- section_11_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- The mechanisms underlying the pathophysiology and treatment of depression and stress-related disorders remain unclear, but studies in depressed patients and rodent models are beginning to yield promising insights.
- study_system
- therapeutic targeting / PV circuits
- section_title
- Species Translation, Human Data, and Disease Models
- evidence_summary
- Study on therapeutic targeting of PV circuits
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2019.03.013", "claim": "Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments", "evidence": "Study on therapeutic targeting of PV circuits", "effect_size": null, "text_access": "abstract_only", "study_system": "therapeutic targeting / PV circuits", "replication_status": "replication_unknown", "claim_source_sentence": "The mechanisms underlying the pathophysiology and treatment of depression and stress-related disorders remain unclear, but studies in depressed patients and rodent models are beginning to yield promising insights.", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:5d79c4a5-08b2-42a6-b622-86a762b915cd" ]
- evidence_refs
[ { "ref": "paper:5d79c4a5-08b2-42a6-b622-86a762b915cd" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }