Details
- scope
- Mouse V1 (visual cortex); paired recordings; layer L2/3
- claim_text
- In Cossell et al. mouse V1 L2/3 paired recordings, neurons with positive response correlations (>0.2) formed connections with median EPSP 1.38 mV, vs. 0.12 mV for negatively correlated pairs (Wilcoxon p = 6.8 × 10⁻⁵).
- section_id
- section_06
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
- effect_size
- 1.38 mV vs 0.12 mV median; p = 6.8 × 10⁻⁵
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-06-connectomic-micons
- source_kind
- review_finding
- source_path
- evidence/section_06_evidence_package.json
- study_system
- Mouse V1 (visual cortex); paired recordings; layer L2/3
- section_title
- 6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates
- evidence_summary
- Stratification of connected-pair EPSPs by response correlation; non-parametric test.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-06-connectomic-micons
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- raw_fields
{ "n": 26, "doi": "10.1038/nature14182", "claim": "In Cossell et al. mouse V1 L2/3 paired recordings, neurons with positive response correlations (>0.2) formed connections with median EPSP 1.38 mV, vs. 0.12 mV for negatively correlated pairs (Wilcoxon p = 6.8 × 10⁻⁵).", "cite_key": "Cossell2015", "evidence": "Stratification of connected-pair EPSPs by response correlation; non-parametric test.", "effect_size": "1.38 mV vs 0.12 mV median; p = 6.8 × 10⁻⁵", "text_access": "fulltext", "study_system": "Mouse V1 (visual cortex); paired recordings; layer L2/3", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Importantly, response correlation was closely related to EPSP amplitude: the strongest connections were found between neuronal pairs with the highest response correlations (;), while neurons with negatively correlated responses tended not to connect or formed only weak connections (response correlation > 0.2, median amplitude of connected pairs: 1.38 mV,= 10; response correlation < 0, median amplitude: 0.12 mV,= 16;= 6.8 × 10, Wilcoxon rank-sum test;).", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "Importantly, response correlation was closely related to EPSP amplitude: the strongest connections were found between neuronal pairs with the highest response correlations (;), while neurons with negatively correlated responses tended not to connect or formed only weak connections (response correlation > 0.2, median amplitude of connected pairs: 1.38 mV,= 10; response correlation < 0, median amplitude: 0.12 mV,= 16;= 6.8 × 10, Wilcoxon rank-sum test;)." }- source_refs
[ "paper:paper-c4ad527c9bfb" ]
- source_span
Importantly, response correlation was closely related to EPSP amplitude: the strongest connections were found between neuronal pairs with the highest response correlations (;), while neurons with negatively correlated responses tended not to connect or formed only weak connections (response correlation > 0.2, median amplitude of connected pairs: 1.38 mV,= 10; response correlation < 0, median amplitude: 0.12 mV,= 16;...
- evidence_refs
[ { "ref": "paper:paper-c4ad527c9bfb" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }