- raw_fields
{
"n": 0,
"doi": "10.7554/eLife.59715",
"claim": "Activity-dependent synaptic plasticity on input and output synapses of PV interneurons generates excitatory-inhibitory neuronal assemblies consistent with mouse V1, producing stimulus-specific competition between pyramidal neurons",
"evidence": "Computational modeling of PV interneuron plasticity in V1",
"effect_size": "Both input and output plasticity required in synergy to form E/I assemblies",
"text_access": "fulltext",
"study_system": "computational model of mouse primary visual cortex",
"replication_status": "single study",
"claim_source_sentence": "Here, we show that activity-dependent synaptic plasticity on input and output synapses of PV interneurons generates a circuit structure that is consistent with mouse V1. Once established, these assemblies produce a stimulus-specific competition between pyramidal neurons.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Computational modeling reveals that both forms of plasticity must act in synergy to form the observed E/I assemblies."
}- source_refs
[
"paper:paper-ce8a09f59a46"
]
- source_span
Here, we show that activity-dependent synaptic plasticity on input and output synapses of PV interneurons generates a circuit structure that is consistent with mouse V1. Once established, these assemblies produce a stimulus-specific competition between pyramidal neurons.
- evidence_refs
[
{
"ref": "paper:paper-ce8a09f59a46"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}