- claim_text
Fast-spiking basket cells (FSBCs) fire with highest frequency and accuracy during cholinergically-induced gamma oscillations compared to axo-axonic cells and regular-spiking basket cells; periodic GABA release from FSBCs generates the oscillatory field potential
- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.4104-10.2010",
"claim": "Fast-spiking basket cells (FSBCs) fire with highest frequency and accuracy during cholinergically-induced gamma oscillations compared to axo-axonic cells and regular-spiking basket cells; periodic GABA release from FSBCs generates the oscillatory field potential",
"evidence": "Single neuron recordings in parallel with LFP during carbachol-induced oscillations in hippocampal slices, plus paired recordings",
"effect_size": "FSBCs fired most frequently and with highest precision among three perisomatic interneuron types",
"text_access": "abstract_only",
"study_system": "rat hippocampal slices, in vitro",
"replication_status": "independently replicated",
"claim_source_sentence": "During these oscillations, FSBCs fired the most with the highest accuracy compared with the discharge of AACs and RSBCs. These results collectively suggest that the rhythmic perisomatic inhibition, generating oscillatory fluctuation in local field potentials after carbachol treatment of hippocampal slices, is the result of periodic GABA release from FSBCs.",
"replication_evidence_dois": [
"10.1146/annurev-neuro-062111-150444"
],
"effect_size_source_sentence": "During these oscillations, FSBCs fired the most with the highest accuracy compared with the discharge of AACs and RSBCs."
}- source_refs
[
"paper:paper-8d634a42e871"
]
- source_span
During these oscillations, FSBCs fired the most with the highest accuracy compared with the discharge of AACs and RSBCs. These results collectively suggest that the rhythmic perisomatic inhibition, generating oscillatory fluctuation in local field potentials after carbachol treatment of hippocampal slices, is the result of periodic GABA release from FSBCs.
- evidence_refs
[
{
"ref": "paper:paper-8d634a42e871"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}