Version history

{
  "scope": "mouse VM thalamus → ALM during cued licking",
  "claim_text": "In trained mice performing a tactile-cued licking task, two-photon imaging shows that ventromedial-thalamic axon terminals in mouse ALM are transiently active during licking and predict the time of the first lick, and chemogenetic/optogenetic perturbation of VM axons demonstrates that VM input facilitates the initiation of cue-triggered and impulsive licking.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.cub.2021.06.089",
    "claim": "In trained mice performing a tactile-cued licking task, two-photon imaging shows that ventromedial-thalamic axon terminals in mouse ALM are transiently active during licking and predict the time of the first lick, and chemogenetic/optogenetic perturbation of VM axons demonstrates that VM input facilitates the initiation of cue-triggered and impulsive licking.",
    "cite_key": "Takahashi2021",
    "evidence": "Two-photon calcium imaging plus chemogenetic and optogenetic manipulation of VM thalamic axons in ALM during a tactile-cued licking task.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "mouse VM thalamus → ALM during cued licking",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Two-photon Ca imaging of VM axons revealed that the majority of the axon terminals in ALM were transiently active during licking. Their activity was predictive of the time of the first lick. Chemogenetic and optogenetic manipulation of VM axons in ALM indicated that VM inputs facilitate the initiation of cue-triggered and impulsive licking in trained mice.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_01",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-01-introduction",
  "source_kind": "review_finding",
  "source_path": "evidence/section_01_evidence_package.json",
  "source_refs": [
    "paper:paper-2f1dac206724"
  ],
  "source_span": "Two-photon Ca imaging of VM axons revealed that the majority of the axon terminals in ALM were transiently active during licking. Their activity was predictive of the time of the first lick. Chemogenetic and optogenetic manipulation of VM axons in ALM indicated that VM inputs facilitate the initiation of cue-triggered and impulsive licking in trained mice.",
  "study_system": "mouse VM thalamus → ALM during cued licking",
  "evidence_refs": [
    {
      "ref": "paper:paper-2f1dac206724"
    }
  ],
  "section_title": "1. Introduction — what \"excitatory recurrence\" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon calcium imaging plus chemogenetic and optogenetic manipulation of VM thalamic axons in ALM during a tactile-cued licking task.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-01-introduction",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}