Details

scope
hippocampal GABAergic interneurons (review)
section_id
section_05_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json
effect_size
~10-15% of hippocampal neuronal population; multiple PV subtypes with shared FS phenotype
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
hippocampal GABAergic interneurons (review)
section_title
Intrinsic Electrophysiology: The Fast-Spiking Phenotype and Its Variants
evidence_summary
Comprehensive review of hippocampal GABAergic interneurons covering development, ion channel expression, and roles in network oscillations.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (6)
claim_text
Hippocampal PV interneurons include multiple morphologically distinct subtypes (basket cells, axo-axonic/chandelier cells, bistratified cells) that share the fast-spiking electrophysiological phenotype but differ in their axonal targeting and circuit roles.
raw_fields
{
  "n": 0,
  "doi": "10.1152/physrev.00007.2017",
  "claim": "Hippocampal PV interneurons include multiple morphologically distinct subtypes (basket cells, axo-axonic/chandelier cells, bistratified cells) that share the fast-spiking electrophysiological phenotype but differ in their axonal targeting and circuit roles.",
  "evidence": "Comprehensive review of hippocampal GABAergic interneurons covering development, ion channel expression, and roles in network oscillations.",
  "effect_size": "~10-15% of hippocampal neuronal population; multiple PV subtypes with shared FS phenotype",
  "text_access": "fulltext",
  "study_system": "hippocampal GABAergic interneurons (review)",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "GABAergic local circuit inhibitory interneurons represent only ~10-15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2016.06.033"
  ],
  "effect_size_source_sentence": "GABAergic local circuit inhibitory interneurons represent only ~10-15% of the total neuronal population."
}
source_refs
[
  "paper:paper-ad1611a9283a"
]
source_span
GABAergic local circuit inhibitory interneurons represent only ~10-15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function.
evidence_refs
[
  {
    "ref": "paper:paper-ad1611a9283a"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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