Version history

{
  "scope": "rodent (review)",
  "claim_text": "Cortical pyramidal neurons are organized in layers with distinct long-range projection profiles: layer 2/3 neurons project between cortical areas, while layer 5/6 neurons additionally innervate subcortical structures, motivating cell-class–specific dissection of corticostriatal circuits.",
  "raw_fields": {
    "n": null,
    "doi": "10.1002/jnr.23978",
    "claim": "Cortical pyramidal neurons are organized in layers with distinct long-range projection profiles: layer 2/3 neurons project between cortical areas, while layer 5/6 neurons additionally innervate subcortical structures, motivating cell-class–specific dissection of corticostriatal circuits.",
    "cite_key": "Gerfen2016",
    "evidence": "Review of intersectional anatomical methods for labeling and recording from layer-specific corticofugal pyramidal neurons.",
    "effect_size": "qualitative — layer-based segregation of cortical projections",
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    "source_cluster_id": "cluster_03",
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    "claim_source_sentence": "Layer 5 cortical pyramidal neurons may be further subdivided into those with projections restricted to the cortex and striatum, bilaterally, and those with projections distributed ipsilaterally within the cortex as well as to subcortical targets including the striatum, thalamus, subthalamic nucleus,",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Subtypes of cortical pyramidal neurons are organized across layers, with those in different layers distinguished by their patterns of axonal projections and connectivity."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json",
  "effect_size": "qualitative — layer-based segregation of cortical projections",
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  "source_span": "Layer 5 cortical pyramidal neurons may be further subdivided into those with projections restricted to the cortex and striatum, bilaterally, and those with projections distributed ipsilaterally within the cortex as well as to subcortical targets including the striatum, thalamus, subthalamic nucleus,",
  "study_system": "rodent (review)",
  "evidence_refs": [
    {
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  "section_title": "The Cortico-Striatal Interface: Topography, Cell Types, and Input Convergence",
  "source_policy": {
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
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  "evidence_summary": "Review of intersectional anatomical methods for labeling and recording from layer-specific corticofugal pyramidal neurons.",
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  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json",
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  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
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