Details
- scope
- rodent, hippocampus, multisite optogenetics in freely behaving animals
- claim_text
- PV interneuron activation paces ensemble spiking during hippocampal ripple oscillations; PV silencing aborts spontaneous ripples
- section_id
- section_08_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- effect_size
- PV activation paced ensemble spiking; PV silencing aborted ripples
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-08
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- closed-loop silencing of pyramidal cells or activation of parvalbumin-(PV) or somatostatin-immunoreactive interneurons aborted spontaneously occurring ripples
- study_system
- rodent, hippocampus, multisite optogenetics in freely behaving animals
- section_title
- In Vivo Dynamics and Behavioural Correlates
- evidence_summary
- Depolarization of nearby pyramidal cells sufficient to induce high-frequency oscillations; focal GABAA blockade abolished ripples; PV activation produced temporally coherent ripple patterns across locations
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-08
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2014.06.023", "claim": "PV interneuron activation paces ensemble spiking during hippocampal ripple oscillations; PV silencing aborts spontaneous ripples", "evidence": "Depolarization of nearby pyramidal cells sufficient to induce high-frequency oscillations; focal GABAA blockade abolished ripples; PV activation produced temporally coherent ripple patterns across locations", "effect_size": "PV activation paced ensemble spiking; PV silencing aborted ripples", "text_access": "fulltext", "study_system": "rodent, hippocampus, multisite optogenetics in freely behaving animals", "replication_status": "independently_replicated", "claim_source_sentence": "closed-loop silencing of pyramidal cells or activation of parvalbumin-(PV) or somatostatin-immunoreactive interneurons aborted spontaneously occurring ripples", "replication_evidence_dois": [ "10.1126/science.1149381" ], "effect_size_source_sentence": "Localized PV interneuron activation paced ensemble spiking, and simultaneous induction of high-frequency oscillations at multiple locations resulted in a temporally coherent pattern mediated by phase-locked interneuron spiking" }- source_refs
[ "paper:paper-208b392bff06" ]
- evidence_refs
[ { "ref": "paper:paper-208b392bff06" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }