- claim_text
In rat frontal cortex L5, paired recordings showed that fast-spiking (FS) interneurons preferentially form reciprocal synaptic connections with pyramidal cells while non-FS interneurons preferentially share L2/3 inputs with co-connected pyramidal cells, integrating inhibitory and excitatory cells into distinct cell-type-specific subnetworks.
- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.2219-09.2009",
"claim": "In rat frontal cortex L5, paired recordings showed that fast-spiking (FS) interneurons preferentially form reciprocal synaptic connections with pyramidal cells while non-FS interneurons preferentially share L2/3 inputs with co-connected pyramidal cells, integrating inhibitory and excitatory cells into distinct cell-type-specific subnetworks.",
"cite_key": "Otsuka2009",
"evidence": "Dual whole-cell recordings combined with focal L2/3 glutamate stimulation in rat frontal cortex.",
"effect_size": "qualitative — FS↔pyramidal reciprocal vs non-FS↔pyramidal common-input",
"text_access": "abstract_only",
"study_system": "rat frontal cortex L5 pyramidal and FS/non-FS interneurons",
"argument_role": "supporting",
"replication_status": "within_lab_replicated",
"claim_source_sentence": "In layer 5 (L5), the probability of reciprocal synaptic connections between pyramidal cells and fast-spiking (FS) interneurons was significantly higher than the probability of reciprocal connections between pyramidal cells and non-FS interneurons.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [
"10.1523/JNEUROSCI.1921-08.2008",
"10.1523/JNEUROSCI.0772-11.2011"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-9aae26e9cfe6"
]
- source_span
In layer 5 (L5), the probability of reciprocal synaptic connections between pyramidal cells and fast-spiking (FS) interneurons was significantly higher than the probability of reciprocal connections between pyramidal cells and non-FS interneurons.
- evidence_refs
[
{
"ref": "paper:paper-9aae26e9cfe6"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}