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- Live5/17/2026, 4:35:28 PM
f1b3a32d857cContent snapshot
{ "scope": "vip-interneurons", "claim_text": "A recurrent network model of mouse V1 captures the locomotion-driven gain change only when locomotion increases feedforward synaptic weights and modulates recurrent weights between VIP/SST/PV/Pyr; pure disinhibition fails when visual stimuli are present.", "raw_fields": { "n": null, "doi": "10.1016/j.neuron.2018.03.037", "year": "2018", "claim": "A recurrent network model of mouse V1 captures the locomotion-driven gain change only when locomotion increases feedforward synaptic weights and modulates recurrent weights between VIP/SST/PV/Pyr; pure disinhibition fails when visual stimuli are present.", "title": "Vision and Locomotion Shape the Interactions between Neuron Types in Mouse Visual Cortex", "journal": "", "species": "mouse", "cite_key": "Dipoppa2018", "evidence": "Two-photon Ca2+ imaging of all four cell classes (Pyr/SST/VIP/PV) + recurrent network model.", "effect_size": "Locomotion required scaling of synaptic weights to reproduce VIP/SST stimulus-dependent responses.", "text_access": "fulltext", "_source_cluster": "cluster_13_neuromodulation", "replication_status": "single_study", "_source_cluster_index": 24, "claim_source_sentence": "The disinhibitory model failed when visual stimuli were present: locomotion increased Sst cell responses to large stimuli and Vip cell responses to small stimuli.", "replication_evidence_dois": [], "effect_size_source_sentence": "Capturing the effects of locomotion, however, required allowing it to increase feedforward synaptic weights and modulate recurrent weights." }, "section_id": "section_08", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json", "effect_size": "Locomotion required scaling of synaptic weights to reproduce VIP/SST stimulus-dependent responses.", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-08-in-vivo-behavior", "source_kind": "review_finding", "source_path": "evidence/section_08_evidence_package.json", "source_refs": [ "paper:paper-f457e091013f" ], "source_span": "The disinhibitory model failed when visual stimuli were present: locomotion increased Sst cell responses to large stimuli and Vip cell responses to small stimuli.", "study_system": null, "evidence_refs": [ { "ref": "paper:paper-f457e091013f" } ], "section_title": "In Vivo Function During Behavior", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Two-photon Ca2+ imaging of all four cell classes (Pyr/SST/VIP/PV) + recurrent network model.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "single_study", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-08-in-vivo-behavior", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }