- raw_fields
{
"n": 0,
"doi": "10.1038/s41380-020-0685-9",
"claim": "Optogenetic and chemogenetic tools targeting PV interneurons and other PFC circuit elements have begun to elucidate contributions of discrete neuronal populations to depression- and anxiety-like behavior",
"evidence": "Review of therapeutic circuit manipulation approaches in depression models",
"effect_size": null,
"text_access": "fulltext",
"study_system": "mouse models of depression and anxiety, PFC circuits",
"replication_status": "replication_unknown",
"claim_source_sentence": "Recently developed optogenetic and chemogenetic tools that allow high fidelity control of neuronal activity in pre-clinical models have begun to elucidate the contributions of the PFC and its circuitry to depression- and anxiety-like behavior.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-ca16efadab86"
]
- source_span
Recently developed optogenetic and chemogenetic tools that allow high fidelity control of neuronal activity in pre-clinical models have begun to elucidate the contributions of the PFC and its circuitry to depression- and anxiety-like behavior.
- evidence_refs
[
{
"ref": "paper:paper-ca16efadab86"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}