The 29 striatal domains feed into 14 SNr and 36 GPe domains and form six closed…

Details

scope: mouse (multi-synaptic anterograde tracing)
claim_text: The 29 striatal domains feed into 14 SNr and 36 GPe domains and form six closed cortico-basal ganglia-thalamic subnetworks; the striatonigral direct pathway converges more than the parallel striatopallidal indirect pathway.
section_id: section_03
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json
effect_size: 14 SNr domains, 36 GPe domains, 6 thalamic domains, 6 closed loops
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-03
source_kind: review_finding
source_path: evidence/section_03_evidence_package.json
source_span: Discussion This work reveals that the canonical cortico–basal ganglia–thalamic network is composed of six parallel subnetworks, each of which is organized by a number of nodes that are precisely and richly interconnected (Fig. 4a ).
study_system: mouse (multi-synaptic anterograde tracing)
section_title: The Cortico-Striatal Interface: Topography, Cell Types, and Input Convergence
evidence_summary: Whole-brain anterograde mapping from striatal domains through GPe, SNr, thalamic nuclei, and cortex; identification of six parallel cortico-basal ganglia-thalamic loops closing back onto originating corticostriatal neurons.
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-03
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": null,
  "doi": "10.1038/s41586-021-03993-3",
  "claim": "The 29 striatal domains feed into 14 SNr and 36 GPe domains and form six closed cortico-basal ganglia-thalamic subnetworks; the striatonigral direct pathway converges more than the parallel striatopallidal indirect pathway.",
  "cite_key": "Foster2021",
  "evidence": "Whole-brain anterograde mapping from striatal domains through GPe, SNr, thalamic nuclei, and cortex; identification of six parallel cortico-basal ganglia-thalamic loops closing back onto originating corticostriatal neurons.",
  "effect_size": "14 SNr domains, 36 GPe domains, 6 thalamic domains, 6 closed loops",
  "text_access": "fulltext",
  "study_system": "mouse (multi-synaptic anterograde tracing)",
  "source_cluster_id": "cluster_03",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Discussion This work reveals that the canonical cortico–basal ganglia–thalamic network is composed of six parallel subnetworks, each of which is organized by a number of nodes that are precisely and richly interconnected (Fig. 4a ).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Following the SNr outputs, we delineate six domains in the parafascicular and ventromedial thalamic nuclei."
}

source_refs

[
  "paper:paper-79995db40fc1"
]

evidence_refs

[
  {
    "ref": "paper:paper-79995db40fc1"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}