Version history

{
  "scope": "mouse; A1, PFC, neocortex; optogenetics, in vivo, slice; Nature",
  "claim_text": "A class of interneurons that express vasoactive intestinal polypeptide (VIP) mediates disinhibitory control in multiple areas of neocortex and is recruited by reinforcement signals.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/nature12676",
    "claim": "A class of interneurons that express vasoactive intestinal polypeptide (VIP) mediates disinhibitory control in multiple areas of neocortex and is recruited by reinforcement signals.",
    "cite_key": "Pi2013",
    "evidence": "In the mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division of labour subserving distinct modes of inhibitory control. A unique mode of inhibitory control may be provided by inhibitory neurons that specifically suppress the firing of other inhibitory neurons. Such disinhibition could lead to the selective amplification of local processing and serve the important computational functions of gating and gain modulation. Although several interneuron populations are k...",
    "effect_size": "Indeed, VIP expression demarcates a small population of all interneurons (~10%), distinct from the two major interneuron populations defined by parvalbumin (Pv) and somatostatin (Som) expression.",
    "text_access": "fulltext",
    "study_system": "mouse; A1, PFC, neocortex; optogenetics, in vivo, slice; Nature",
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    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "claim_rewritten_from_source": true,
    "effect_size_source_sentence": "Indeed, VIP expression demarcates a small population of all interneurons (~10%), distinct from the two major interneuron populations defined by parvalbumin (Pv) and somatostatin (Som) expression."
  },
  "section_id": "section_09",
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  "effect_size": "Indeed, VIP expression demarcates a small population of all interneurons (~10%), distinct from the two major interneuron populations defined by parvalbumin (Pv) and somatostatin (Som) expression.",
  "review_repo": "ComputationalReviewRecurrence",
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  "study_system": "mouse; A1, PFC, neocortex; optogenetics, in vivo, slice; Nature",
  "evidence_refs": [
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  "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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  "evidence_summary": "In the mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division of labour subserving distinct modes of inhibitory control. A unique mode of inhibitory control may be provided by inhibitory neurons that specifically suppress the firing of other inhibitory neurons. Such disinhibition could lead to the selective amplification of local processing and serve the important computational functions of gating and gain modulation. Although several interneuron populations are k...",
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}