- claim_text
Chandelier cells (axo-axonic cells), a PV-expressing subtype, share the fast-spiking phenotype with basket cells but target exclusively the axon initial segment of pyramidal cells, providing a unique form of inhibitory control over action potential generation.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2016.06.033",
"claim": "Chandelier cells (axo-axonic cells), a PV-expressing subtype, share the fast-spiking phenotype with basket cells but target exclusively the axon initial segment of pyramidal cells, providing a unique form of inhibitory control over action potential generation.",
"evidence": "Multiple studies characterizing chandelier cell electrophysiology showing fast-spiking properties with distinct axonal targeting.",
"effect_size": "chandelier cells share FS phenotype with basket cells but target exclusively AIS",
"text_access": "fulltext",
"study_system": "mouse and primate neocortex",
"replication_status": "independently_replicated",
"claim_source_sentence": "The Pvalb subclass can be split into basket (and related) cells and chandelier cells.",
"replication_evidence_dois": [
"10.1093/cercor/bhn198"
],
"effect_size_source_sentence": "the Pvalb subclass can be split into basket (and related) cells and chandelier cells."
}- source_refs
[
"paper:paper-53c8505de50f"
]
- evidence_refs
[
{
"ref": "paper:paper-53c8505de50f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}