Version history

{
  "scope": "theoretical/review across rodent and human cortex",
  "claim_text": "A theoretical framework (GAMER) proposes that four classes of interneurons—PV, VIP, SST, and NOS—exploit endogenous cortical gamma oscillations to perform active vasomotor and homeostatic control, linking gamma rhythms to circuit maintenance and brain health.",
  "raw_fields": {
    "n": null,
    "doi": "10.7554/elife.100238",
    "pmid": "39565646",
    "year": "2024",
    "claim": "A theoretical framework (GAMER) proposes that four classes of interneurons—PV, VIP, SST, and NOS—exploit endogenous cortical gamma oscillations to perform active vasomotor and homeostatic control, linking gamma rhythms to circuit maintenance and brain health.",
    "pmcid": "PMC11578591",
    "title": "The gamma rhythm as a guardian of brain health.",
    "authors": "",
    "journal": "",
    "cite_key": "Ichim2024",
    "evidence": "Review and synthesis of gamma rhythm mechanisms, gamma entrainment using sensory stimulation (GENUS) literature, and proposal of vasomotor coupling.",
    "cluster_id": "cluster_09_oscillations",
    "effect_size": null,
    "figure_data": [],
    "text_access": "fulltext",
    "study_system": "theoretical/review across rodent and human cortex",
    "cited_by_count": 21,
    "_source_cluster": "cluster_09_oscillations",
    "replication_status": "single-study",
    "_source_cluster_index": 5,
    "claim_source_sentence": "We propose that four classes of interneurons, namely those expressing parvalbumin (PV), vasointestinal peptide (VIP), somatostatin (SST), and nitric oxide synthase (NOS) take advantage of endogenous gamma to perform active vasomotor control that maintains homeostasis in the neuronal tissue.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
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  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json",
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  "review_repo": "ComputationalReviewVIP",
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  "source_path": "evidence/section_10_evidence_package.json",
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    "paper:paper-4c7255d4433c"
  ],
  "source_span": "We propose that four classes of interneurons, namely those expressing parvalbumin (PV), vasointestinal peptide (VIP), somatostatin (SST), and nitric oxide synthase (NOS) take advantage of endogenous gamma to perform active vasomotor control that maintains homeostasis in the neuronal tissue.",
  "study_system": "theoretical/review across rodent and human cortex",
  "evidence_refs": [
    {
      "ref": "paper:paper-4c7255d4433c"
    }
  ],
  "section_title": "Oscillatory Dynamics and Temporal Coordination",
  "source_policy": {
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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  "evidence_summary": "Review and synthesis of gamma rhythm mechanisms, gamma entrainment using sensory stimulation (GENUS) literature, and proposal of vasomotor coupling.",
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  "replication_status": "single-study",
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}