Cortico-subthalamic projections from motor cortex are required for visually gui…

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scope: mouse cortico-STN projections, visually guided locomotion
claim_text: Cortico-subthalamic projections from motor cortex are required for visually guided locomotor control in mice, with optogenetic perturbation of cortico-STN inputs disrupting on-line trajectory adjustments
section_id: section_04
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
effect_size
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-04
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: We thus developed a task in which head-fixed mice run to a visual landmark, then stop and wait to collect the reward, and examined the projections from the secondary motor cortex (M2) to STN.
study_system: mouse cortico-STN projections, visually guided locomotion
section_title: Striatal Output Pathways: Direct, Indirect, and Beyond
evidence_summary: Optogenetic and pharmacological manipulation of cortico-STN inputs during visually guided locomotion in mice
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-04
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1016/j.celrep.2022.111139",
  "claim": "Cortico-subthalamic projections from motor cortex are required for visually guided locomotor control in mice, with optogenetic perturbation of cortico-STN inputs disrupting on-line trajectory adjustments",
  "cite_key": "Adam2022",
  "evidence": "Optogenetic and pharmacological manipulation of cortico-STN inputs during visually guided locomotion in mice",
  "effect_size": "",
  "text_access": "fulltext",
  "study_system": "mouse cortico-STN projections, visually guided locomotion",
  "source_cluster_id": "cluster_04",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We thus developed a task in which head-fixed mice run to a visual landmark, then stop and wait to collect the reward, and examined the projections from the secondary motor cortex (M2) to STN.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-6c7949828c61"
]

evidence_refs

[
  {
    "ref": "paper:paper-6c7949828c61"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
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Cortico-subthalamic projections from motor cortex are required for visually gui…

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