Chandelier cells have a depolarizing effect on pyramidal neurons at resting mem…

Details

scope: mouse somatosensory cortex brain slices, Nkx2.1Cre MADM mice
claim_text: Chandelier cells have a depolarizing effect on pyramidal neurons at resting membrane potential in neocortex
section_id: section_06_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-06
source_kind: review_finding
source_path: evidence/section_06_evidence_package.json
source_span: chandelier PSPs have in every case a reversal potential that is depolarized from rest.
study_system: mouse somatosensory cortex brain slices, Nkx2.1Cre MADM mice
section_title: Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
evidence_summary: Paired recordings in perforated patch and cell-attached configurations showed chandelier PSPs consistently depolarized from rest
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: contested
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-06
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.3389/neuro.04.015.2009",
  "claim": "Chandelier cells have a depolarizing effect on pyramidal neurons at resting membrane potential in neocortex",
  "evidence": "Paired recordings in perforated patch and cell-attached configurations showed chandelier PSPs consistently depolarized from rest",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse somatosensory cortex brain slices, Nkx2.1Cre MADM mice",
  "replication_status": "contested",
  "claim_source_sentence": "chandelier PSPs have in every case a reversal potential that is depolarized from rest.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.0605-23.2023",
    "10.1016/j.celrep.2017.06.030"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-c803cdbd5cbd"
]

evidence_refs

[
  {
    "ref": "paper:paper-c803cdbd5cbd"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Chandelier cells have a depolarizing effect on pyramidal neurons at resting mem…

Details

Replication

Discussion