Version history

{
  "scope": "Two cohorts of healthy adults; multimodal MRI",
  "claim_text": "Structure-function coupling decreases and its temporal variance increases along the unimodal-to-transmodal and granular-to-agranular cortical gradients in humans, with myelination and excitation-inhibition balance acting as complementary mediators.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41467-023-41686-9",
    "claim": "Structure-function coupling decreases and its temporal variance increases along the unimodal-to-transmodal and granular-to-agranular cortical gradients in humans, with myelination and excitation-inhibition balance acting as complementary mediators.",
    "cite_key": "Fotiadis2023",
    "evidence": "Structure-function coupling decreases and its temporal variance increases along the unimodal-to-transmodal and granular-to-agranular cortical gradients in humans, with myelination and excitation-inhibition balance acting as complementary mediators.",
    "effect_size": "1",
    "text_access": "fulltext",
    "study_system": "Two cohorts of healthy adults; multimodal MRI",
    "source_cluster_id": "cluster_07",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Our findings are consistent across six complementary processing pipelines: 1) SFC and its temporal variance respectively decrease and increase across the unimodal-transmodal and granular-agranular gradients; 2) increased myelination and lower EI-ratio are associated with more rigid SFC and restricted moment-to-moment SFC fluctuations; 3) a gradual shift from EI-ratio to myelination as the principal predictor of SFC occurs when traversing from granular to agranular cortical regions.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Our findings are consistent across six complementary processing pipelines: 1) SFC and its temporal variance respectively decrease and increase across the unimodal-transmodal and granular-agranular gradients; 2) increased myelination and lower EI-ratio are associated with more rigid SFC and restricted moment-to-moment SFC fluctuations; 3) a gradual shift from EI-ratio to myelination as the principal predictor of SFC occurs when traversing from granular to agranular cortical regions."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json",
  "effect_size": "1",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-08",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-e110cf9048dd"
  ],
  "source_span": "Our findings are consistent across six complementary processing pipelines: 1) SFC and its temporal variance respectively decrease and increase across the unimodal-transmodal and granular-agranular gradients; 2) increased myelination and lower EI-ratio are associated with more rigid SFC and restricted moment-to-moment SFC fluctuations; 3) a gradual shift from EI-ratio to myelination as the principal predictor of SFC...",
  "study_system": "Two cohorts of healthy adults; multimodal MRI",
  "evidence_refs": [
    {
      "ref": "paper:paper-e110cf9048dd"
    }
  ],
  "section_title": "Cortical Association Connectome: Intra-Cortical Loops and Modules",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Structure-function coupling decreases and its temporal variance increases along the unimodal-to-transmodal and granular-to-agranular cortical gradients in humans, with myelination and excitation-inhibition balance acting as complementary mediators.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-08",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}