Details

scope
mouse GPe, BAC-Npas1 transgenic line, immunohistochemistry
claim_text
In mouse GPe, parvalbumin- and Npas1-expressing neurons constitute non-overlapping cell classes (~55% and ~27% of total) — providing a transgenic, molecularly anchored classification of GPe heterogeneity.
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
effect_size
PV+ ≈ 55% of GPe neurons; Npas1+ ≈ 27% of GPe neurons; non-overlapping
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
study_system
mouse GPe, BAC-Npas1 transgenic line, immunohistochemistry
section_title
Pallidal Organization and the Disinhibition Principle
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.4672-14.2015",
  "claim": "In mouse GPe, parvalbumin- and Npas1-expressing neurons constitute non-overlapping cell classes (~55% and ~27% of total) — providing a transgenic, molecularly anchored classification of GPe heterogeneity.",
  "cite_key": "Hernandez2015b",
  "evidence": "",
  "effect_size": "PV+ ≈ 55% of GPe neurons; Npas1+ ≈ 27% of GPe neurons; non-overlapping",
  "text_access": "abstract_only",
  "study_system": "mouse GPe, BAC-Npas1 transgenic line, immunohistochemistry",
  "source_cluster_id": "cluster_04",
  "replication_status": "replicated",
  "claim_source_sentence": "Using a combinatorial transgenic and immunohistochemical approach, we discovered that parvalbumin-expressing neurons and Npas1-expressing neurons in the GPe represent two nonoverlapping cell classes, amounting to 55% and 27% of the total GPe neuron population, respectively.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2012.04.027",
    "10.1523/jneurosci.4662-14.2015"
  ],
  "effect_size_source_sentence": "Using a combinatorial transgenic and immunohistochemical approach, we discovered that parvalbumin-expressing neurons and Npas1-expressing neurons in the GPe represent two nonoverlapping cell classes, amounting to 55% and 27% of the total GPe neuron population, respectively."
}
source_refs
[
  "paper:paper-14204ea3a58f"
]
source_span
Using a combinatorial transgenic and immunohistochemical approach, we discovered that parvalbumin-expressing neurons and Npas1-expressing neurons in the GPe represent two nonoverlapping cell classes, amounting to 55% and 27% of the total GPe neuron population, respectively.
evidence_refs
[
  {
    "ref": "paper:paper-14204ea3a58f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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