- claim_text
Across mouse sensory, motor and frontal cortex, corticostriatal projections from layer-5 IT-type and PT-type neurons differ in topographic precision: IT-type neurons show higher topographic stereotypy than PT-type neurons, and IT-type projections from interconnected cortical areas correlate more strongly in their striatal targeting — supporting parallel basal-ganglia loops.
- raw_fields
{
"n": null,
"doi": "10.1038/s41467-018-05780-7",
"claim": "Across mouse sensory, motor and frontal cortex, corticostriatal projections from layer-5 IT-type and PT-type neurons differ in topographic precision: IT-type neurons show higher topographic stereotypy than PT-type neurons, and IT-type projections from interconnected cortical areas correlate more strongly in their striatal targeting — supporting parallel basal-ganglia loops.",
"cite_key": "Hooks2018",
"evidence": "Cre-driver-restricted AAV labelling of IT and PT L5 neurons across sensory, motor and frontal areas with quantitative mapping of striatal terminal fields.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse cortex L5 IT vs PT corticostriatal projections",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "Topographic organization differs between IT-type and PT-type neurons, including injections in the same site, with IT-type neurons having higher topographic stereotypy than PT-type neurons. Furthermore, IT-type projections from interconnected cortical areas have stronger correlations in corticostriatal targeting than PT-type projections do.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-470beb0644b3"
]
- source_span
Topographic organization differs between IT-type and PT-type neurons, including injections in the same site, with IT-type neurons having higher topographic stereotypy than PT-type neurons. Furthermore, IT-type projections from interconnected cortical areas have stronger correlations in corticostriatal targeting than PT-type projections do.
- evidence_refs
[
{
"ref": "paper:paper-470beb0644b3"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}