Details

scope
human brain, review
claim_text
PV interneurons primarily exhibit chandelier and basket cell morphologies, originate from the medial ganglionic eminence, and are distributed across neocortical layers I-VI with predominance in layers II and III
section_id
section_04_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-04
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
study_system
human brain, review
section_title
Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond
evidence_summary
PV interneurons primarily exhibit chandelier and basket cell morphologies, originate from the medial ganglionic eminence, and are distributed across neocortical layers I-VI with predominance in layers II and III
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-04
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.brainres.2025.150141",
  "claim": "PV interneurons primarily exhibit chandelier and basket cell morphologies, originate from the medial ganglionic eminence, and are distributed across neocortical layers I-VI with predominance in layers II and III",
  "evidence": "PV interneurons primarily exhibit chandelier and basket cell morphologies, originate from the medial ganglionic eminence, and are distributed across neocortical layers I-VI with predominance in layers II and III",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "human brain, review",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Among them, parvalbumin-positive interneurons primarily exhibit chandelier and basket cell morphologies and are characterized by a fast-spiking firing pattern. These cells originate from the medial ganglionic eminence during human brain development and are widely distributed across neocortical layers I-VI, with a predominance in layers II and III.",
  "replication_evidence_dois": [
    "10.1093/texcom/tgaa026",
    "10.1523/jneurosci.0432-23.2023"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-b0544e9fbfc3"
]
source_span
Among them, parvalbumin-positive interneurons primarily exhibit chandelier and basket cell morphologies and are characterized by a fast-spiking firing pattern. These cells originate from the medial ganglionic eminence during human brain development and are widely distributed across neocortical layers I-VI, with a predominance in layers II and III.
evidence_refs
[
  {
    "ref": "paper:paper-b0544e9fbfc3"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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