Details

scope
human PD patients, simultaneous EEG + STN DBS recording
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_13_evidence_package.json
effect_size
STN-DBS abolishes mediofrontal cortical conflict-related slowing of decisions
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-13
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
study_system
human PD patients, simultaneous EEG + STN DBS recording
section_title
Computational Models of Loop Function
evidence_summary
Combined EEG and STN-DBS recording in PD patients during a probabilistic decision task.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-13
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_13_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (6)
claim_text
Subthalamic deep brain stimulation in Parkinson's patients abolishes the mediofrontal-cortical signature that ordinarily slows decisions under conflict, consistent with computational models in which the STN raises the cortico-basal-ganglia decision threshold.
raw_fields
{
  "n": 14,
  "doi": "10.1038/nn.2925",
  "claim": "Subthalamic deep brain stimulation in Parkinson's patients abolishes the mediofrontal-cortical signature that ordinarily slows decisions under conflict, consistent with computational models in which the STN raises the cortico-basal-ganglia decision threshold.",
  "cite_key": "Cavanagh2011",
  "evidence": "Combined EEG and STN-DBS recording in PD patients during a probabilistic decision task.",
  "effect_size": "STN-DBS abolishes mediofrontal cortical conflict-related slowing of decisions",
  "text_access": "abstract_only",
  "study_system": "human PD patients, simultaneous EEG + STN DBS recording",
  "source_cluster_id": "cluster_12",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Although medial prefrontal cortex (mPFC) is broadly implicated in effortful control over behavior, the subthalamic nucleus (STN) is specifically thought to contribute by acting as a brake on cortico-striatal function during decision conflict, buying time until the right decision can be made.",
  "replication_evidence_dois": [
    "10.3389/fnins.2012.00009",
    "10.1098/rstb.2013.0481"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-25903cab54e0"
]
source_span
Although medial prefrontal cortex (mPFC) is broadly implicated in effortful control over behavior, the subthalamic nucleus (STN) is specifically thought to contribute by acting as a brake on cortico-striatal function during decision conflict, buying time until the right decision can be made.
evidence_refs
[
  {
    "ref": "paper:paper-25903cab54e0"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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