Version history

{
  "scope": "mouse V1",
  "claim_text": "Here we demonstrate that SOM neurons are active at a greater dynamic ACh range than VIP and L1 neurons, and cholinergic inputs to the superficial layers of primary visual cortex (V1) act via SOM neurons (but not VIP and L1 neurons) to activate a specific inhibitory-excitatory cortical circuit that drives alterations of brain state synchrony and neuronal correlations.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/nn.4002",
    "year": "2015",
    "claim": "Here we demonstrate that SOM neurons are active at a greater dynamic ACh range than VIP and L1 neurons, and cholinergic inputs to the superficial layers of primary visual cortex (V1) act via SOM neurons (but not VIP and L1 neurons) to activate a specific inhibitory-excitatory cortical circuit that drives alterations of brain state synchrony and neuronal correlations.",
    "title": null,
    "journal": "Nature neuroscience",
    "cite_key": "Chen2015a",
    "evidence": "An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity",
    "effect_size": "10 – 100 Hz",
    "text_access": "fulltext",
    "first_author": "Chen",
    "study_system": "mouse V1",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "author_list_short": "Chen, Sugihara, Sur",
    "replication_status": "replicated",
    "_source_cluster_index": 19,
    "claim_source_sentence": "Here we demonstrate that SOM neurons are active at a greater dynamic ACh range than VIP and L1 neurons, and cholinergic inputs to the superficial layers of primary visual cortex (V1) act via SOM neurons (but not VIP and L1 neurons) to activate a specific inhibitory-excitatory cortical circuit that drives alterations of brain state synchrony and neuronal correlations.",
    "replication_evidence_dois": [
      "10.1038/nm.4274",
      "10.1038/s41467-019-13244-9"
    ],
    "effect_size_source_sentence": "1a-e ), including post-stimulation decrease of low frequency events (<10 Hz) and increase of high frequency events (10 – 100 Hz) ( Fig."
  },
  "section_id": "section_01",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "effect_size": "10 – 100 Hz",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-01-introduction",
  "source_kind": "review_finding",
  "source_path": "evidence/section_01_evidence_package.json",
  "source_refs": [
    "paper:paper-2c3589e2f07a"
  ],
  "source_span": "Here we demonstrate that SOM neurons are active at a greater dynamic ACh range than VIP and L1 neurons, and cholinergic inputs to the superficial layers of primary visual cortex (V1) act via SOM neurons (but not VIP and L1 neurons) to activate a specific inhibitory-excitatory cortical circuit that drives alterations of brain state synchrony and neuronal correlations.",
  "study_system": "mouse V1",
  "evidence_refs": [
    {
      "ref": "paper:paper-2c3589e2f07a"
    }
  ],
  "section_title": "Introduction",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-01-introduction",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}