Autophagy regulates PV interneuron excitability and memory function; disruption…

Details

scope: mouse, PV-specific autophagy manipulation
claim_text: Autophagy regulates PV interneuron excitability and memory function; disruption of autophagy in PV cells impairs their fast-spiking properties
section_id: section_09_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-09
source_kind: review_finding
source_path: evidence/section_09_evidence_package.json
source_span: Autophagy regulates PVALB (parvalbumin) interneuron excitability and memory.
study_system: mouse, PV-specific autophagy manipulation
section_title: Brain Region and Layer Context: Beyond Primary Sensory Cortex
evidence_summary: Autophagy regulates PV interneuron excitability and memory function; disruption of autophagy in PV cells impairs their fast-spiking properties
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-09
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1080/15548627.2025.2597463",
  "claim": "Autophagy regulates PV interneuron excitability and memory function; disruption of autophagy in PV cells impairs their fast-spiking properties",
  "evidence": "Autophagy regulates PV interneuron excitability and memory function; disruption of autophagy in PV cells impairs their fast-spiking properties",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse, PV-specific autophagy manipulation",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Autophagy regulates PVALB (parvalbumin) interneuron excitability and memory.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-2d0a2cc36a25"
]

evidence_refs

[
  {
    "ref": "paper:paper-2d0a2cc36a25"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Autophagy regulates PV interneuron excitability and memory function; disruption…

Details

Replication

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