Details

scope
mouse neocortex (review)
claim_text
PV interneurons are the largest group of cortical interneurons, comprising ~40% of cortical GABAergic cells, and include both basket cells and chandelier cells with distinct morphological and functional properties.
section_id
section_02_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
effect_size
~40% of cortical GABAergic neurons
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-02
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
study_system
mouse neocortex (review)
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
Comprehensive review of cortical GABAergic interneuron properties, demonstrating that the PV subclass includes basket and chandelier cells as morphologically distinct subtypes.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-02
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neuron.2016.06.033",
  "claim": "PV interneurons are the largest group of cortical interneurons, comprising ~40% of cortical GABAergic cells, and include both basket cells and chandelier cells with distinct morphological and functional properties.",
  "evidence": "Comprehensive review of cortical GABAergic interneuron properties, demonstrating that the PV subclass includes basket and chandelier cells as morphologically distinct subtypes.",
  "effect_size": "~40% of cortical GABAergic neurons",
  "text_access": "fulltext",
  "study_system": "mouse neocortex (review)",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Evidence collected to date suggests the presence of four major subclasses of cortical GABAergic neurons: parvalbumin (Pvalb)-positive, somatostatin (Sst)-positive, vasoactive intestinal peptide (Vip)-positive cells, and cells that express 5-hydroxytryptamine receptor 3A but lack Vip.",
  "replication_evidence_dois": [
    "10.1016/j.cell.2017.08.032",
    "10.1016/j.neuron.2018.10.009"
  ],
  "effect_size_source_sentence": "the Pvalb subclass can be split into basket (and related) cells and chandelier cells"
}
source_refs
[
  "paper:paper-53c8505de50f"
]
source_span
Evidence collected to date suggests the presence of four major subclasses of cortical GABAergic neurons: parvalbumin (Pvalb)-positive, somatostatin (Sst)-positive, vasoactive intestinal peptide (Vip)-positive cells, and cells that express 5-hydroxytryptamine receptor 3A but lack Vip.
evidence_refs
[
  {
    "ref": "paper:paper-53c8505de50f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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