Details

scope
vip-interneurons
claim_text
VIP-mediated disinhibition operates orthogonally to cross-modal attentional modulation in mouse cortex, indicating disinhibition and attention rely on partly separable circuits.
section_id
section_09
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-09-cross-areas
source_kind
review_finding
source_path
evidence/section_09_evidence_package.json
section_title
VIP Interneurons Across Brain Regions
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-09-cross-areas
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2023.11.006",
  "year": 2023,
  "claim": "VIP-mediated disinhibition operates orthogonally to cross-modal attentional modulation in mouse cortex, indicating disinhibition and attention rely on partly separable circuits.",
  "title": null,
  "region": "S1/A1",
  "cite_key": "Myersjoseph2024",
  "effect_size": null,
  "text_access": "abstract_only",
  "conflict_flag": true,
  "fig_table_ref": null,
  "_source_cluster": "cluster_08_brain_regions",
  "evidence_gap_flag": false,
  "unreplicated_flag": false,
  "replication_status": null,
  "_source_cluster_index": 11,
  "claim_source_sentence": "Attentional modulation of sensory processing is a key feature of cognition; however, its neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of pyramidal cells through vasoactive intestinal peptide (VIP) and somatostatin (SOM)-positive interneurons. However, the interaction of attentional modulation and VIP-SOM disinhibition has never been directly tested. We used all-optical methods to bi-directionally manipulate VIP interneuron activity as mice performed a cro"
}
source_refs
[
  "paper:paper-bcc613ccccd9"
]
source_span
Attentional modulation of sensory processing is a key feature of cognition; however, its neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of pyramidal cells through vasoactive intestinal peptide (VIP) and somatostatin (SOM)-positive interneurons. However, the interaction of attentional modulation and VIP-SOM disinhibition has never been directly tested. We used all-optical method...
evidence_refs
[
  {
    "ref": "paper:paper-bcc613ccccd9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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