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- Live5/17/2026, 4:35:28 PM
cb6e99fd27c7Content snapshot
{ "scope": "mouse postnatal cortical FS interneurons (P7-P40)", "claim_text": "Fast-spiking interneuron identity emerges through postnatal transcriptional maturation involving bidirectional regulation of thousands of genes between P7 and P40.", "raw_fields": { "n": 0, "doi": "10.1523/jneurosci.0105-09.2009", "claim": "Fast-spiking interneuron identity emerges through postnatal transcriptional maturation involving bidirectional regulation of thousands of genes between P7 and P40.", "evidence": "", "effect_size": "thousands of genes bidirectionally regulated over first 4 postnatal weeks", "text_access": "abstract_only", "study_system": "mouse postnatal cortical FS interneurons (P7-P40)", "replication_status": "replication_unknown", "claim_source_sentence": "We found that the intrinsic and synaptic physiology of FS cells undergoes profound regulation over the first 4 postnatal weeks and that these changes are correlated with primarily monotonic but bidirectional transcriptional regulation of thousands of genes.", "replication_evidence_dois": [], "effect_size_source_sentence": "these changes are correlated with primarily monotonic but bidirectional transcriptional regulation of thousands of genes belonging to multiple functional classes" }, "section_id": "section_02_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json", "effect_size": "thousands of genes bidirectionally regulated over first 4 postnatal weeks", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-02", "source_kind": "review_finding", "source_path": "evidence/section_02_evidence_package.json", "source_refs": [ "paper:paper-591943f1ad14" ], "source_span": "We found that the intrinsic and synaptic physiology of FS cells undergoes profound regulation over the first 4 postnatal weeks and that these changes are correlated with primarily monotonic but bidirectional transcriptional regulation of thousands of genes.", "study_system": "mouse postnatal cortical FS interneurons (P7-P40)", "evidence_refs": [ { "ref": "paper:paper-591943f1ad14" } ], "section_title": "Molecular Identity and Transcriptomic Taxonomy", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-02", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }